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Best Solutions for Uterine Fibroids, Consider Myfembree and Oriahann

New medications for uterine fibroid treatment includes both Myfembree and Oriahann.

Women who have small, minimally or not-symptomatic uterine fibroids can try other solutions such as botanicals. Here’s a review of the information from PubMed.

The most important step is to determine if you have uterine fibroids is find a provider who will monitor you over time. You need to have your provider monitor your uterine fibroids size, location, growth pattern, and whether you have normal menstrual bleeding patterns.

Other reasons to treat uterine fibroids include chronic lower urinary tract or bowel symptoms, infertility, prior adverse pregnancy outcome, sexual complaints, or bulk-related symptoms. Bluk related symptoms from uterine fibroid include pelvic pressure, pelvic pain, pelvic heaviness, or fullness in the vaginal, vulvar or pelvic region.

Thyroid problems, uterine endometrial lining disorders, and bleeding disorders can all be the cause of heavy bleeding that is not related to uterine fibroids…but can occur at the same time as uterine fibroids: so be checked for these conditions as well!

Orhiann has elagolix, estradiol and northindrone in each pill. It is indicated for the treatment of heavy menstrual bleeding in premenopausal women with uterine fibroids.

Myfembree has relugolix, estradiol, and norethindrone, and is also indicated for the same treatment reasons as Orhiann.

Both provide excellent contraceptive protection when taken consistently, and they would treat endometriosis as well.

Both medications may be considered second line therapies for uterine fibroids, because of their side effect profile, more traditional medicines can be tried first.

Both medications would have potent protection against endometriosis as well as uterine fibroid treatment.

All medication treatments including DepoProvera, contraceptive pills and IUDs can help the symptoms of bleeding. The best treatments for pelvic pressure are usually procedures such as hysterectomy or myomectomy (removing fibroids but keeping the uterus).

Both medications have the same amount of estrogen and the progesterone northindrone, and both have the same warnings about potential blood clotting disorders and vascular events including DVT strokes, myocardial infarctions, and pulmonary embolism.

It is recommended that women have assessment of their bone density at baseline and thereafter, and not use the medications for over 24 months because of potential bone loss.

Possible side effects of these medications include hot flashes, sweating, lack of menstrual periods and the inability to recognize that you are pregnant, uterine bleeding, hair loss and decreased libido.

But the best news is that women may notice that their periods are literally half as heavy as they were prior to using the medication.

Women who are anemic because of the amount of bleeding can find that they have their anemia stabilized as the bleeding is so well controlled.


Suzanne Trupin, MD, Board Certified Obstetrician and Gynecologist and owner of Women's Health Practice, Hada Cosmetic Medicine, and Hatha Yoga and Fitness

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